Méngoo jël
Jàppale bu am solo: Mazdudede
kategori produit
1.Dual {1} ay agoniste:
agonist yi ci GLP{{1}11 (1}1 peptide-1) ak reseptëri GCGR (moytu reseptër glucagon).
2. Njaboot yi:
Kontrolu glucose bu deret ci 2 xeetu jabet mellitus (T2DM)
Yaxxum yaram/jëfandikoo ci yenn réew wala gox)
Dañu jàpp ni mekaniismu physical:
Mazdude dafay am njeexital ci paj mi ci ñaari jëf yii:
1.GLP-1 reseptër bi: Diggal insulin, dafay tere glucagon bi génn, ba noppi wàññi suukër si ci deret ji. Delay gastrik bi dafay jeex, ba noppi yokk yëg-yëgu mat.
2.GCGR reseptër bi: Fexe am doole ci wàllu energie, dafay gëna yokk metabolism bu grees, ba noppi gëna baaxal gluconogenis hepatic bi.
Njariñu produit yi:
1. Ñaari mbir: Buñu ko méngale ak benn garabu GLP-1 (lu melni semmaglutide), yokk ci aktivasioŋ ci reseptëru GCGR mën na indi wàññikug diisaay bu gëna am solo ak njeexitalu yokkute ci metabolism.
2. {1} ràndewu ci diir bi: pikiir bi gëna ndaw benn yoon ci ayu-bis bi ngir gëna mëna topp malaad bi.
3. Njariñu metabolism bu mat sëkk: Lu weesu suukër si ci deret ji, mën na wàññi itam lipid yi ci deret ji, wàññi diisaay bi, ba noppi gëna yokk feebar bi ci xëtëru xëtër bi (NAFLD), ak ñoom seen.
4. Efe hypoglycéic: Ci malaad yi am diabet type 2, HbA1c (hemoglobine glycated) dafay wàññeeku bu baax (jàngat yiñ def ci klinik yi dañuy wane 1,5% ba 2.0%).
5. Effe buy wàññi poid bi: Li gëna néew ci wàññi yaram ci malaad yu ëpp yaram mën na yegg ba 10% ba 15% (3} groupe bu kawe- dose).
6. Kaaraange: Reaction yu baaxul yu bari ñooy reactions gastro-intestinal yu woyof wala yu yam (lu melni xel muusea ak biir burhea), te loolu dafay nuru yooyu garab yu mel noonu.
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